Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.57 |
| ▸ | OXTR | P30559 | 2/20 | 0.57 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991132 | 0.88 | AVPR1A (0.72) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6989274 | 0.88 | AVPR2 (0.54) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL7349185 | 0.87 | AVPR1A (0.59) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6967016 | 0.87 | AVPR1A (0.64) | AVPR1AAVPR2OXTR | |
| SCHEMBL5945610 | 0.86 | AVPR2 (0.76) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6990495 | 0.86 | AVPR2 (0.58) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6995083 | 0.86 | AVPR2 (0.58) | AVPR1AAVPR2OXTR | |
| SCHEMBL6989699 | 0.85 | RAB9A (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL6989484 | 0.85 | AVPR2 (0.70) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL8506093 | 0.81 | AVPR1A (0.49) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| US-5856564-A | CHEMICAL INTERMEDIATE FOR VASOPRESSIN ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5723606-A | Condensed benzazepine derivative and pharmaceutical composition thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |