Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | OXTR | P30559 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989274 | 0.90 | AVPR2 (0.54) | AVPR2AVPR1AOXTRALDH1A1 | |
| SCHEMBL6989699 | 0.89 | RAB9A (0.55) | AVPR2AVPR1ARAB9AOXTRMEN1 | |
| SCHEMBL6991132 | 0.87 | AVPR1A (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL7354363 | 0.86 | AVPR1A (0.74) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558289 | 0.86 | AVPR2 (0.60) | AVPR2AVPR1AMAPTRAB9AOXTR | |
| SCHEMBL7349230 | 0.86 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL6989758 | 0.86 | AVPR1A (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL7349185 | 0.85 | AVPR1A (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL6989484 | 0.85 | AVPR2 (0.70) | AVPR2AVPR1AOXTR | |
| SCHEMBL7349028 | 0.85 | AVPR1A (0.76) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| US-5856564-A | CHEMICAL INTERMEDIATE FOR VASOPRESSIN ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5723606-A | Condensed benzazepine derivative and pharmaceutical composition thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |