⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277528 | 0.75 | — | — | |
| SCHEMBL3566233 | 0.75 | — | — | |
| SCHEMBL6986695 | 0.74 | — | — | |
| SCHEMBL272224 | 0.73 | — | — | |
| SCHEMBL271257 | 0.71 | — | — | |
| SCHEMBL9930814 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL3667041 | 0.67 | ALDH1A1 (0.37) | — | |
| SCHEMBL3664297 | 0.65 | CA2 (0.31) | — | |
| SCHEMBL13790225 | 0.62 | — | — | |
| SCHEMBL3734197 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |