Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.65 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.65 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989817 | 0.86 | AVPR1A (0.66) | AVPR1AAVPR1BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6987161 | 0.84 | AVPR1A (0.73) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL8798138 | 0.83 | AVPR1A (0.77) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8797050 | 0.83 | AVPR1A (0.59) | AVPR1AAVPR1BAVPR2MAPTPOLB | |
| SCHEMBL8796877 | 0.82 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2KMT2AMEN1 | |
| SCHEMBL8797460 | 0.82 | AVPR1A (0.62) | AVPR1AAVPR1BAVPR2TP53KMT2A | |
| SCHEMBL7365160 | 0.81 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2SMN1; SMN2TP53 | |
| SCHEMBL7348119 | 0.81 | RAB9A (0.64) | RAB9A | |
| SCHEMBL6991783 | 0.79 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2MAPTALDH1A1 | |
| SCHEMBL6989132 | 0.79 | AVPR1A (0.85) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |