Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989852 | 1.00 | KDM4E (0.47) | KDM4ELMNAMAPK1DRD3DRD2 | |
| SCHEMBL6768552 | 0.92 | KDM4E (0.47) | KDM4ELMNAMAPK1DRD3DRD2 | |
| SCHEMBL6768554 | 0.92 | KDM4E (0.47) | KDM4ELMNAMAPK1DRD3DRD2 | |
| SCHEMBL6992602 | 0.90 | HTR1A (0.48) | DRD3DRD2DRD4 | |
| SCHEMBL6992608 | 0.90 | HTR1A (0.48) | DRD3DRD2DRD4 | |
| SCHEMBL6993246 | 0.90 | KDM4E (0.45) | KDM4ELMNAMAPK1DRD3DRD2 | |
| SCHEMBL6993251 | 0.90 | KDM4E (0.45) | KDM4ELMNAMAPK1DRD3DRD2 | |
| SCHEMBL6994634 | 0.89 | DRD3 (0.59) | DRD3DRD2DRD4 | |
| SCHEMBL6994638 | 0.89 | DRD3 (0.59) | DRD3DRD2DRD4 | |
| SCHEMBL6989077 | 0.88 | HTR1A (0.49) | DRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557526-B1 | PYRROLOAZEPINE COMPOUND | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5399557-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |