Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082384 | 1.00 | NR4A1 (0.60) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL11909813 | 0.85 | NR4A1 (0.60) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL766944 | 0.84 | KDM4E (0.57) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL28379027 | 0.84 | NR4A1 (0.53) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL29117786 | 0.81 | PLK1 (0.53) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL6514661 | 0.80 | PTPN1 (0.53) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL6514650 | 0.80 | PTPN1 (0.53) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL4624841 | 0.80 | NR4A1 (0.53) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| SCHEMBL7559405 | 0.79 | MEN1 (0.47) | NR4A1NR4A2NR4A3CDC25BMEN1 | |
| Naphthoic Acid SCHEMBL6442333 | 0.79 | NR4A1 (0.88) | NR4A1NR4A2NR4A3CDC25BPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973636-B1 | TRANSPARENT ARTICLE WITH RADIAL REFRACTIVE INDEX GRADIENT AND PROCESS FOR ITS MANUFACTURE | ESSILOR INT (FR) | 2003-01-02 | — | — | EP | claimed |