SCHEMBL6990064

SCHEMBL6990064

Cc1ccc(S(=O)(=O)N=C=S)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.50
PRSS1 P07477 2/20 0.50
PRSS2 P07478 2/20 0.50
PRSS3 P35030 2/20 0.50
GAA P10253 3/20 0.48
HTT P42858 1/20 0.47
LMNA P02545 1/20 0.47
CYP2C19 P33261 1/20 0.47
DDAH1 O94760 1/20 0.45
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
CA3 P07451 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22302 0.81 F2 (0.52) F2PRSS1PRSS2PRSS3GAA
SCHEMBL25376416 0.79 F2 (0.50) F2PRSS1PRSS2PRSS3CA1
SCHEMBL26037514 0.79 F2 (0.50) F2PRSS1PRSS2PRSS3GAA
SCHEMBL6416400 0.78 KEAP1 (0.44) HTTLMNADDAH1CA12CA1
SCHEMBL484742 0.78 CA1 (0.63) LMNACYP2C19CA1CA2CA9
SCHEMBL28209363 0.78 F2 (0.48) F2PRSS1PRSS2PRSS3GAA
SCHEMBL5950368 0.78 F2 (0.48) F2PRSS1PRSS2PRSS3GAA
SCHEMBL2412815 0.76 F2 (0.55) F2PRSS1PRSS2PRSS3GAA
SCHEMBL5138891 0.75 F2 (0.59) F2PRSS1PRSS2PRSS3GAA
SCHEMBL10884771 0.75 F2 (0.46) F2PRSS1PRSS2PRSS3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746543-A Method for isolating pure cultured vascular endothelial cells, medium for maintaining characteristics of vascular endothelial cells, and culture method comprising same 延世大学校产学协力团 2022-07-12 CN claimed
CN-108877975-B Neutron shielding protective material 湘潭大学 2022-03-22 CN claimed
CN-111521667-B Method for detecting rare earth elements in magnetite 中国科学院地质与地球物理研究所 2020-11-20 CN claimed
CN-111413189-B Method for detecting trace elements in pyrite 中国科学院地质与地球物理研究所 2020-10-20 CN claimed
CN-111521667-A Method for detecting rare earth elements in magnetite 中国科学院地质与地球物理研究所 2020-08-11 CN claimed
CN-111413189-A Method for detecting trace elements in pyrite 中国科学院地质与地球物理研究所 2020-07-14 CN claimed
CN-101735127-A Method for preparing tosyl isothiocyanate WEST BRANCH OF ZHEJIANG UNIVER 2010-06-16 CN claimed
US-12637697-B2 Compositions and methods for generating physiological X chromosome inactivation CHILDREN'S MEDICAL CENTER CORPORATION (US) 2026-05-26 US disclosed
EP-4719052-A1 GENETICALLY MODIFIED PORCINE CELL, GENETICALLY MODIFIED PIG AND METHODS OF PRODUCING SAME Wolf, Eckhard (DE) 2026-04-08 EP disclosed
EP-4626483-A1 SURFACE MODIFIED CARBON NANOTUBES AND USES THEREOF Luna Labs USA, LLC (US) 2025-10-08 EP disclosed
US-20250185233-A1 SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-06-05 US disclosed
CN-119968417-A Bovine blastocyst-like structure and application thereof 路易斯安娜州立大学监测委员会,农业和机械学院 2025-05-09 CN disclosed
CN-119790143-A Materials and methods for bioengineering iPSC populations 詹森生物科技公司 2025-04-08 CN disclosed
EP-0819118-B1 POTASSIUM ION CHANNEL BLOCKERS POLYCHIP PHARMACEUTICALS PTY (AU) 2002-09-18 EP disclosed
WO-2001087863-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-11-22 WO disclosed
US-5929082-A SULFONYL(THIO)UREA AND SULFONYLGUANIDINE COMPOUNDS; TREATMENT OF DIABETES, CARDIAC ARRHYTHMIAS, ISCHEMIA, HYPOXIC CARDIOVASCUALR DISORDERS AND CANCER POLYCHIP PHARMACEUTICALS PTY LTD (AU) 1999-07-27 US disclosed
EP-0819118-A4 POTASSIUM ION CHANNEL BLOCKERS POLYCHIP PHARMACEUTICALS PTY (AU) 1998-04-29 EP disclosed
EP-0819118-A1 POTASSIUM ION CHANNEL BLOCKERS Polychip Pharmaceuticals Pty. Ltd. (AU) 1998-01-21 EP disclosed
WO-1996030341-A1 POTASSIUM ION CHANNEL BLOCKERS POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) 1996-10-03 WO disclosed
US-4288454-A Antiviral 1-adamantyl-3-(phenylsulfonyl)thioureas HOFFMAN-LA ROCHE INC. (US) 1981-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637697-B2 Compositions and methods for generating physiological X chromosome inactivation KDM6B, KDM1B, KDM6A F2 4624/4885PRSS1 3097/4885PRSS2 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.