SCHEMBL484742

SCHEMBL484742

O=S(=O)(N=C=S)c1ccc(N=C=S)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
P2RY6 Q15077 3/20 0.45
MIF P14174 2/20 0.45
ALDH1A1 P00352 4/20 0.44
RAD51 Q06609 4/20 0.44
HSD17B10 Q99714 3/20 0.44
CYP3A4 P08684 3/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
KDM4E B2RXH2 2/20 0.44
USP2 O75604 2/20 0.44
LTA P01374 2/20 0.44
P2RX3 P56373 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CA9 Q16790 1/20 0.41
RAD1 O60671 1/20 0.40
KEAP1 Q14145 2/20 0.38
NFE2L2 Q16236 2/20 0.38
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5654352 0.89 CA1 (0.59) CA1CA2P2RY6MIFALDH1A1
SCHEMBL483832 0.81 CA1 (0.70) CA1CA2P2RY6MIFALDH1A1
SCHEMBL668791 0.78 CA1 (0.66) CA1CA2P2RY6MIFALDH1A1
SCHEMBL31315339 0.78 CA1 (0.66) CA1CA2P2RY6MIFALDH1A1
SCHEMBL6196292 0.78 CA1 (0.66) CA1CA2P2RY6MIFALDH1A1
SCHEMBL25376416 0.78 F2 (0.50) CA1CA2MIFALDH1A1CA9
SCHEMBL6990064 0.78 F2 (0.50) CA1CA2ALDH1A1HPGDCA9
SCHEMBL1476527 0.78 CA2 (1.00) CA1CA2P2RY6MIFALDH1A1
SCHEMBL2891113 0.78 CA1 (0.66) CA1CA2P2RY6MIFALDH1A1
SCHEMBL8694424 0.78 CA1 (0.66) CA1CA2P2RY6MIFALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396248-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2024-07-10 EP disclosed
US-11965092-B2 Polyurethane composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
US-11965108-B2 Composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
CN-117897424-A Aqueous polyurethane urea dispersions 科思创德国股份有限公司 2024-04-16 CN disclosed
US-20240034828-A1 Aqueous Polyurethane Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-02-01 US disclosed
CN-110869355-B Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition 株式会社德山 2023-11-14 CN disclosed
WO-2023210418-A1 THERMOSETTING COMPOSITION, CURED PRODUCT, AND OPTICAL MEMBER 富士フイルム株式会社 2023-11-02 WO disclosed
EP-4259683-A1 AQUEOUS POLYURETHANE UREA DISPERSION Covestro Deutschland AG (DE) 2023-10-18 EP disclosed
EP-3841139-B1 A POLYURETHANE COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-10-04 EP disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-0676429-A2 Composition for urethane-base plastic lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-11 EP disclosed
EP-0665219-A1 Polythiol, process for producing same, sulfur-containing urethane-base resin prepared from the polythiol, process for producing the resin, and lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-08-02 EP disclosed
EP-0630927-A2 Optical urethane resin Takeda Chemical Industries, Ltd. (JP) 1994-12-28 EP disclosed
EP-0351073-B1 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed