SCHEMBL6990424

SCHEMBL6990424

CC(CO)CC(C)Cc1ccc(C(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.44
ESR1 P03372 3/20 0.41
IDO1 P14902 2/20 0.41
ESR2 Q92731 2/20 0.41
ACACB O00763 2/20 0.40
PTGS1 P23219 3/20 0.38
PTGS2 P35354 3/20 0.38
LMNA P02545 2/20 0.38
CYP2C9 P11712 2/20 0.38
AKR1C3 P42330 2/20 0.38
CXCR1 P25024 2/20 0.38
CXCR2 P25025 2/20 0.38
ALB P02768 1/20 0.38
ALOX5 P09917 1/20 0.38
RARB P10826 1/20 0.38
ADRB3 P13945 1/20 0.38
NFKB1 P19838 1/20 0.38
HTR2A P28223 1/20 0.38
NR1I3 Q14994 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20610522 0.90 ESR1 (0.45) TRPA1ESR1IDO1ESR2ACACB
SCHEMBL1219827 0.90 ESR1 (0.45) TRPA1ESR1IDO1ESR2ACACB
SCHEMBL9455527 0.82 IDO1 (0.45) ESR1IDO1ESR2ACACBPTGS1
SCHEMBL17171333 0.80 TRPA1 (0.59) TRPA1
SCHEMBL110694 0.80 TRPA1 (0.59) TRPA1
SCHEMBL6989159 0.78 TP53 (0.50) TRPA1ACACBLMNATSHREPHX1
SCHEMBL24648909 0.76 IDO1 (0.48) TRPA1ESR1IDO1ESR2ACACB
SCHEMBL24648911 0.76 IDO1 (0.48) TRPA1ESR1IDO1ESR2ACACB
SCHEMBL18570895 0.75 IDO1 (0.47) ESR1IDO1ESR2ACACBPTGS1
SCHEMBL8840397 0.74 IDO1 (0.50) ESR1IDO1ESR2ACACBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908439-B1 Use of substituted 5-phenyl-pentanols as flavour and perfume HAARMANN & REIMER GMBH (DE) 2003-01-02 EP disclosed
EP-0908439-A1 Use of substituted 5-phenyl-pentanols as flavour and perfume HAARMANN & REIMER GMBH (DE) 1999-04-14 EP disclosed