Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157160 | 0.86 | DRD2 (0.53) | DRD2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5338207 | 0.85 | BRD9 (0.47) | DRD2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5393894 | 0.83 | ACACB (0.42) | DRD2ACACBACACANAMPTL3MBTL1 | |
| SCHEMBL7540124 | 0.83 | SETDB1 (0.55) | DRD2HTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8335595 | 0.82 | SETDB1 (0.53) | DRD2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14355994 | 0.81 | BRD9 (0.48) | DRD2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5332614 | 0.81 | HTR1A (0.51) | DRD2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30159605 | 0.79 | KCNA5 (0.56) | KCNA5NAMPTL3MBTL1KDM4A | |
| SCHEMBL8018113 | 0.79 | KCNA5 (0.56) | KCNA5NAMPTL3MBTL1KDM4A | |
| SCHEMBL24120598 | 0.79 | SMN1; SMN2 (0.52) | ACACBACACANAMPTL3MBTL1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368340-A1 | PIPERAZINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002059108-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |