Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.65 |
| ▸ | CES1 | P23141 | 3/20 | 0.65 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990865 | 1.00 | CES2 (0.65) | CES2CES1MAOBGAAL3MBTL1 | |
| SCHEMBL17102810 | 0.92 | CES2 (0.57) | CES2CES1MAOBGAAL3MBTL1 | |
| SCHEMBL15747690 | 0.92 | CES2 (0.57) | CES2CES1MAOBGAAL3MBTL1 | |
| SCHEMBL18962475 | 0.86 | CES2 (0.50) | CES2CES1GAAL3MBTL1AR | |
| SCHEMBL928924 | 0.85 | CES2 (0.63) | CES2CES1L3MBTL1ALDH1A1CYP2C19 | |
| SCHEMBL2846957 | 0.84 | GAA (0.68) | CES2CES1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL30051056 | 0.84 | GAA (0.68) | CES2CES1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL3490146 | 0.84 | GAA (0.68) | CES2CES1GAAL3MBTL1ALDH1A1 | |
| Water SCHEMBL2325340 | 0.83 | CES2 (0.61) | CES2CES1L3MBTL1ALDH1A1CYP2C19 | |
| SCHEMBL23804649 | 0.81 | CYP3A4 (0.62) | MAOBL3MBTL1ARALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921119-B1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0921119-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-09 | — | — | EP | disclosed |