SCHEMBL23804649

SCHEMBL23804649

O=C(/C=C/c1ccc(O)cc1)c1ccc(F)cc1F

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.62
MAPT P10636 3/20 0.62
CYP2C9 P11712 2/20 0.62
NFKB1 P19838 2/20 0.62
CYP2C19 P33261 2/20 0.62
CHRNA7 P36544 2/20 0.62
P4HB P07237 2/20 0.62
MEN1 O00255 2/20 0.62
HPGD P15428 2/20 0.62
KMT2A Q03164 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
TP53 P04637 2/20 0.62
ALOX15 P16050 2/20 0.62
MAPK1 P28482 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
GMNN O75496 1/20 0.62
LMNA P02545 1/20 0.62
ESR1 P03372 1/20 0.62
MMP1 P03956 1/20 0.62
GBA1 P04062 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233251 1.00 CYP3A4 (0.62) CYP3A4MAPTCYP2C9NFKB1CYP2C19
SCHEMBL25196348 0.85 MAOB (0.66) CYP3A4MAPTCYP2C9NFKB1CYP2C19
SCHEMBL25216445 0.85 TNFRSF1A (0.57) CYP3A4MAPTNFKB1P4HBTDP1
SCHEMBL25193684 0.84 MAOB (0.61) CYP3A4MAPTP4HBMEN1HPGD
SCHEMBL25218131 0.81 MAOB (0.61) MAPTP4HBMEN1HPGDKMT2A
SCHEMBL25214713 0.81 MAPT (0.58) MAPTNFKB1P4HBMEN1HPGD
SCHEMBL31233147 0.81 MAOB (0.61) MAPTP4HBMEN1HPGDKMT2A
SCHEMBL25197224 0.81 MAPT (0.58) MAPTNFKB1P4HBMEN1HPGD
SCHEMBL25231544 0.81 MAOB (0.61) MAPTP4HBMEN1HPGDKMT2A
SCHEMBL31233418 0.81 MAOB (0.61) MAPTP4HBMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2021182896-A1 INDUCED BROWN FAT DIFFERENTIATION COMPOSITION COMPRISING ISOLIQUIRITIGENIN DERIVATIVE 가톨릭관동대학교산학협력단 2021-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CYP3A4 928/4885MAPT 3297/4885CYP2C9 124/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CYP3A4 1589/4885MAPT 3512/4885CYP2C9 1237/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CYP3A4 1589/4885MAPT 3512/4885CYP2C9 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.