Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6993414 | 0.99 | KDM4E (0.42) | MEN1BLMKMT2ACHRM3PDE4A | |
| Hydrochloric Acid SCHEMBL6966987 | 0.88 | KCNH3 (0.42) | MEN1BLMKMT2ACHRM3PDE4A | |
| SCHEMBL6997622 | 0.87 | MEN1 (0.45) | MEN1BLMKMT2ACHRM3PDE4A | |
| SCHEMBL6996668 | 0.86 | AXL (0.40) | KMT2ACHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL6997347 | 0.86 | KDM4E (0.45) | MEN1BLMKMT2ACHRM3PDE4A | |
| Hydrochloric Acid SCHEMBL6992368 | 0.85 | AXL (0.39) | KMT2ACHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7000650 | 0.82 | PDE4A (0.42) | MEN1KMT2ACHRM3PDE4APDE4B | |
| SCHEMBL7000651 | 0.80 | MEN1 (0.37) | MEN1BLMKMT2AKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL6991716 | 0.79 | KDM4E (0.38) | MEN1BLMKMT2AKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL8801771 | 0.79 | KDM4E (0.37) | MEN1BLMKMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |
| CN-1102144-C | Noval pyrimidine derivatives and prepn. processes thereof | YUHAN CORP (KR) | 2003-02-26 | — | — | CN | disclosed |