Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6997347 | 0.99 | KDM4E (0.45) | MEN1KMT2ABLMCHRM3PDE4A | |
| SCHEMBL6990874 | 0.87 | MEN1 (0.42) | MEN1KMT2ABLMCHRM3PDE4A | |
| Hydrochloric Acid SCHEMBL6993414 | 0.86 | KDM4E (0.42) | MEN1KMT2ABLMCHRM3PDE4A | |
| SCHEMBL6996918 | 0.85 | AXL (0.42) | KMT2ACHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL6990621 | 0.84 | AXL (0.41) | KMT2ACHRM3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL6966987 | 0.84 | KCNH3 (0.42) | MEN1KMT2ABLMCHRM3PDE4A | |
| SCHEMBL7821547 | 0.82 | LMNA (0.65) | MEN1KMT2ABLMKDM4EMAPK1 | |
| SCHEMBL6991702 | 0.81 | CHRM3 (0.46) | MEN1KMT2ACHRM3PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL8117259 | 0.81 | KCNH3 (0.38) | MEN1KMT2ABLMKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL8111169 | 0.81 | KCNH3 (0.38) | MEN1KMT2ABLMKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |