SCHEMBL6991190

SCHEMBL6991190

CCNNCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
IDO1 P14902 2/20 0.48
THRB P10828 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TP53 P04637 1/20 0.48
HPGD P15428 2/20 0.47
ALOX12 P18054 2/20 0.47
ALPL P05186 1/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SIGMAR1 Q99720 2/20 0.43
HTT P42858 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
ADH1B P00325 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7339049 0.98 MAPT (0.56) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL1792873 0.87 IDO1 (0.60) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL25962733 0.86 CYP3A4 (0.48) CYP3A4MAPTKDM4EIDO1THRB
Hydrochloric Acid SCHEMBL7340226 0.84 MAPT (0.62) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL2893366 0.81 MEN1 (0.50) CYP3A4MAPTKDM4EIDO1THRB
Hydrochloric Acid SCHEMBL11560498 0.79 MAPT (0.52) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL11129280 0.78 HDAC3 (0.51) CYP3A4MAPTKDM4EMEN1KMT2A
SCHEMBL2146 0.77 MEN1 (0.64) CYP3A4MAPTKDM4EIDO1THRB
Benzene SCHEMBL7471176 0.77 MEN1 (0.64) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL3501486 0.77 CYP3A4 (0.61) CYP3A4MAPTKDM4EIDO1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1037633-B1 ANTIVIRAL COMPOUNDS IAF BIOCHEM INT (CA) 2003-09-10 EP claimed
CN-1283995-A Antiviral compounds IAF BIOCHEM INT (CA) 2001-02-14 CN claimed
EP-1037633-A1 ANTIVIRAL COMPOUNDS BIOCHEM PHARMA INC (CA) 2000-09-27 EP claimed
WO-1999029318-A1 ANTIVIRAL COMPOUNDS BIOCHEM PHARMA INC. (CA) 1999-06-17 WO claimed
US-20200290990-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2020-09-17 US disclosed
CN-105267066-B Method for treating hair and kit therefor 知识产权全资有限公司 2019-06-11 CN disclosed
US-6399631-B1 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS PFIZER INC. 2002-06-04 US disclosed
CN-1069643-C Naphthyridine derivatives and their analogues inhibiting cytomegalovirus IAF BIOCHEM INT (CA) 2001-08-15 CN disclosed
CN-1283995-A Antiviral compounds IAF BIOCHEM INT (CA) 2001-02-14 CN disclosed
EP-1037633-A1 ANTIVIRAL COMPOUNDS BIOCHEM PHARMA INC (CA) 2000-09-27 EP disclosed
WO-1999029318-A1 ANTIVIRAL COMPOUNDS BIOCHEM PHARMA INC. (CA) 1999-06-17 WO disclosed
CN-1218473-A Naphthyridine derivatives and their analogues inhibiting cytomegalovirus IAF BIOCHEM INT (CA) 1999-06-02 CN disclosed
US-3997544-A Plant growth regulant carbamoylphosphonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-14 US disclosed
US-3981870-A Plant growth regulant carbamoylphosphonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-21 US disclosed
US-3975464-A PLANT GROWTH REGULATOR E. I. DUPONT DE NEMOURS AND COMPANY (US) 1976-08-17 US disclosed
US-3952074-A PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200290990-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS CYP3A4 720/4885MAPT 3694/4885KDM4E 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.