Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000925 | 0.91 | PARP1 (0.42) | PARP1SMYD3GAAUSP2 | |
| SCHEMBL6999457 | 0.90 | PARP1 (0.42) | PARP1SMYD3HSD17B10 | |
| SCHEMBL6996238 | 0.90 | PARP1 (0.41) | PARP1SMYD3PDE3BPDE3AHTR1A | |
| SCHEMBL6995124 | 0.89 | PARP1 (0.41) | PARP1SMYD3HSD17B10HTR1AHTR7 | |
| SCHEMBL7003521 | 0.87 | PARP1 (0.39) | PARP1SMYD3PDE3BPDE3AHTR1A | |
| SCHEMBL7003826 | 0.87 | PARP1 (0.39) | PARP1SMYD3PDE3BPDE3AL3MBTL1 | |
| SCHEMBL7001819 | 0.87 | PARP1 (0.39) | PARP1SMYD3PDE3BPDE3AUSP2 | |
| SCHEMBL7001012 | 0.86 | PARP1 (0.40) | PARP1SMYD3PDE3BPDE3A | |
| SCHEMBL6996225 | 0.86 | PARP1 (0.39) | PARP1SMYD3GAA | |
| SCHEMBL6994403 | 0.84 | PARP1 (0.41) | PARP1SMYD3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | disclosed |