Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826569 | 0.93 | KMT2A (0.56) | KMT2AMEN1NPY5RUTS2RMAPT | |
| SCHEMBL27604176 | 0.79 | KMT2A (0.57) | KMT2AMEN1NPY5RUTS2RMAPT | |
| SCHEMBL6826899 | 0.70 | NPY5R (0.48) | KMT2AMEN1NPY5RUTS2RMAPT | |
| SCHEMBL6826587 | 0.67 | KMT2A (0.48) | KMT2AMEN1NPY5RMAPTNPC1 | |
| SCHEMBL1149958 | 0.66 | MEN1 (1.00) | KMT2AMEN1NPY5RMAPTLMNA | |
| SCHEMBL7974800 | 0.66 | MEN1 (0.64) | KMT2AMEN1NPY5RMAPTNPC1 | |
| SCHEMBL18622105 | 0.65 | ALDH1A1 (0.55) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL6827505 | 0.65 | KMT2A (0.41) | KMT2AMEN1NPY5RMAPTNPC1 | |
| SCHEMBL6827501 | 0.64 | MEN1 (0.54) | KMT2AMEN1NPY5RMAPTNPC1 | |
| SCHEMBL27604175 | 0.64 | MEN1 (0.44) | KMT2AMEN1NPY5RMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |