Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6991632 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL6991320 | 0.95 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL6991324 | 0.95 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| Oxalic Acid SCHEMBL6990281 | 0.88 | HRH3 (0.58) | ALDH1A1KMT2AMAPK1KDM4ELMNA | |
| Oxalic Acid SCHEMBL7000093 | 0.88 | HRH3 (0.58) | ALDH1A1KMT2AMAPK1KDM4ELMNA | |
| Oxalic Acid SCHEMBL6992367 | 0.86 | KDM4E (0.48) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| Oxalic Acid SCHEMBL6992364 | 0.86 | KDM4E (0.48) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| Oxalic Acid SCHEMBL6998099 | 0.86 | KDM4E (0.48) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| Oxalic Acid SCHEMBL6994123 | 0.86 | MEN1 (0.43) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| Oxalic Acid SCHEMBL6996118 | 0.86 | MEN1 (0.43) | ALDH1A1KMT2AMEN1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |