Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002128 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDPADI4TUBB4ATUBB | |
| SCHEMBL8182316 | 0.82 | PADI4 (0.56) | ALDH1A1HPGDPADI4TUBB4ATUBB | |
| SCHEMBL6998713 | 0.82 | MAPT (0.60) | ALDH1A1HPGDPADI4KDM4EGAA | |
| SCHEMBL8189447 | 0.77 | PADI4 (0.51) | ALDH1A1HPGDPADI4TUBB4ATUBB | |
| SCHEMBL4827488 | 0.74 | CYP1A2 (0.62) | ALDH1A1HPGDKDM4EPOLBHSD17B10 | |
| SCHEMBL6995868 | 0.74 | KDM4E (0.64) | ALDH1A1HPGDGSK3AGSK3BKDM4E | |
| SCHEMBL10648743 | 0.73 | MAPT (0.59) | ALDH1A1HPGDPADI4TUBB4ATUBB | |
| SCHEMBL7825662 | 0.72 | PADI4 (0.57) | ALDH1A1HPGDPADI4TUBB4ATUBB | |
| SCHEMBL18019742 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL15060149 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HPGDTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| EP-1003724-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | Aventis Pharma Deutschland GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1997037977-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-16 | — | — | WO | disclosed |