Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993576 | 0.86 | CYP4A11 (0.35) | PPARAPPARG | |
| SCHEMBL7218505 | 0.80 | THRA (0.37) | PPARAPPARG | |
| SCHEMBL27824398 | 0.79 | EPHX2 (0.36) | PPARAPPARGGPR119 | |
| SCHEMBL6988448 | 0.77 | LSS (0.35) | — | |
| SCHEMBL1161006 | 0.72 | EPHX2 (0.38) | — | |
| SCHEMBL6991041 | 0.72 | GPR119 (0.34) | GPR119 | |
| SCHEMBL3986151 | 0.71 | EPHX2 (0.37) | — | |
| SCHEMBL4586631 | 0.71 | EPHX2 (0.37) | — | |
| SCHEMBL7421738 | 0.69 | POLB (0.32) | — | |
| SCHEMBL9720181 | 0.69 | CA12 (0.45) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349833-A1 | INDOLE AND DIHYDROINDOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002044149-A1 | INDOLE AND DIHYDROINDOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-06 | — | — | WO | disclosed |