Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991832 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6990211 | 0.91 | DAO (0.41) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6990213 | 0.91 | DAO (0.41) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6996475 | 0.86 | ALDH1A1 (0.33) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6996478 | 0.86 | ALDH1A1 (0.33) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6994987 | 0.79 | KDM4E (0.42) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6994989 | 0.79 | KDM4E (0.42) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL6997601 | 0.77 | HTT (0.44) | ALDH1A1CYP1A2CYP2C19MAPTTSHR | |
| SCHEMBL6997598 | 0.77 | HTT (0.44) | ALDH1A1CYP1A2CYP2C19MAPTTSHR | |
| SCHEMBL6994524 | 0.68 | DAO (0.48) | ALDH1A1CYP1A2CYP2C19MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |