Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991997 | 0.88 | AVPR2 (0.59) | AVPR2 | |
| SCHEMBL6988600 | 0.87 | GAA (0.52) | MEN1KMT2A | |
| SCHEMBL8557382 | 0.86 | AVPR2 (0.50) | AVPR1AAVPR2OXTRMEN1KMT2A | |
| SCHEMBL6967016 | 0.83 | AVPR1A (0.64) | AVPR1AAVPR2OXTR | |
| SCHEMBL6991132 | 0.82 | AVPR1A (0.72) | AVPR1AAVPR2OXTR | |
| SCHEMBL7331304 | 0.82 | KMT2A (0.48) | AVPR1AAVPR2MEN1KMT2APOLB | |
| SCHEMBL6987460 | 0.80 | AVPR1A (0.71) | AVPR1AAVPR2OXTRMEN1KMT2A | |
| SCHEMBL6992874 | 0.80 | PDCD1 (0.53) | AVPR2 | |
| SCHEMBL8820413 | 0.80 | AVPR2 (0.56) | AVPR1AAVPR2OXTRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6996579 | 0.79 | AVPR2 (0.49) | AVPR1AAVPR2OXTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| US-5856564-A | CHEMICAL INTERMEDIATE FOR VASOPRESSIN ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5723606-A | Condensed benzazepine derivative and pharmaceutical composition thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |