Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 9/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988600 | 0.89 | GAA (0.52) | — | |
| SCHEMBL6991997 | 0.88 | AVPR2 (0.59) | PDCD1CD274AVPR2 | |
| Hydrochloric Acid SCHEMBL6994116 | 0.80 | PDCD1 (0.48) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL6992001 | 0.80 | AVPR1A (0.50) | AVPR2 | |
| SCHEMBL7021778 | 0.80 | PDE4A (0.59) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL7019627 | 0.80 | PDE4A (0.59) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL25561797 | 0.77 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL31399210 | 0.76 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL31399227 | 0.76 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6995083 | 0.76 | AVPR2 (0.58) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |