Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992001 | 0.88 | AVPR1A (0.50) | AVPR2 | |
| SCHEMBL6992874 | 0.88 | PDCD1 (0.53) | AVPR2PDCD1CD274 | |
| SCHEMBL7331308 | 0.82 | AVPR2 (0.54) | AVPR2PDCD1CD274 | |
| SCHEMBL6988600 | 0.80 | GAA (0.52) | — | |
| SCHEMBL25561676 | 0.80 | PDE4A (0.49) | — | |
| Hydrochloric Acid SCHEMBL6996577 | 0.80 | AVPR2 (0.48) | AVPR2PDCD1CD274 | |
| SCHEMBL6990990 | 0.76 | AVPR2 (0.57) | AVPR2 | |
| SCHEMBL6967016 | 0.75 | AVPR1A (0.64) | AVPR2 | |
| SCHEMBL25561797 | 0.75 | PDE4A (0.61) | — | |
| SCHEMBL31399110 | 0.75 | L3MBTL1 (0.47) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |