Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 12/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992046 | 1.00 | PTPN1 (0.50) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL6992056 | 0.75 | PTPN1 (0.51) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL1248780 | 0.71 | PIM1 (0.83) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL1248782 | 0.71 | PIM1 (0.83) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL12891790 | 0.71 | PIM1 (0.83) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL6183585 | 0.69 | MEN1 (0.60) | HPGDPIM1PIM3PIM2MAOA | |
| SCHEMBL6183587 | 0.69 | MEN1 (0.60) | HPGDPIM1PIM3PIM2MAOA | |
| SCHEMBL4206382 | 0.69 | PIM1 (0.64) | HPGDPIM1PIM3PIM2MAOA | |
| SCHEMBL4035316 | 0.69 | PIM1 (0.64) | HPGDPIM1PIM3PIM2MAOA | |
| SCHEMBL4035319 | 0.69 | PIM1 (0.64) | HPGDPIM1PIM3PIM2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |