Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995129 | 0.78 | LMNA (0.49) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6698689 | 0.78 | TACR1 (0.55) | TACR1MEN1KMT2A | |
| SCHEMBL19002456 | 0.76 | BLM (0.47) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27883950 | 0.75 | RPS6KB1 (0.44) | ALDH1A1POLB | |
| SCHEMBL22032535 | 0.74 | NOTUM (0.41) | MEN1KMT2A | |
| SCHEMBL15103260 | 0.73 | RPS6KB1 (0.44) | ALDH1A1POLB | |
| SCHEMBL22032379 | 0.73 | RPS6KB1 (0.44) | ALDH1A1POLB | |
| SCHEMBL2708207 | 0.73 | RPS6KB1 (0.44) | ALDH1A1POLB | |
| SCHEMBL6408955 | 0.72 | TACR1 (0.49) | TACR1MEN1KMT2A | |
| SCHEMBL4972856 | 0.71 | POLB (0.46) | ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823906-B1 | PIPERAZINO DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORP (US) | 2003-07-09 | — | — | EP | disclosed |
| US-5981520-A | USEFUL FOR TREATING ASTHMA, BRONCHOSPASM, ALLERGIES, ANXIETY, COUGHING OR PAIN | SCHERING CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0823906-A1 | PIPERAZINO DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034864-A1 | PIPERAZINO DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-11-07 | — | — | WO | disclosed |