Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993570 | 0.92 | ADORA1 (0.84) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7719502 | 0.91 | ADORA1 (0.83) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6993678 | 0.90 | GAA (0.82) | ADORA1MAPTMEN1KMT2ALMNA | |
| Tinoridine SCHEMBL24761 | 0.90 | ADORA1 (1.00) | ADORA1MAPTMEN1KMT2ALMNA | |
| Tinoridine SCHEMBL217049 | 0.89 | ADORA1 (0.98) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6990993 | 0.86 | ADORA1 (0.75) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6993930 | 0.82 | MAPT (0.72) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7000413 | 0.82 | GAA (0.82) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6993348 | 0.82 | ADORA1 (0.71) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14234268 | 0.81 | ADORA1 (0.84) | ADORA1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927184-B1 | 3-SUBSTITUTED PYRIDO 4',3':4,5]THIENO 2,3-D]PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6387912-B1 | STROKE THERAPY | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6222034-B1 | AS SEROTININ RECEPTOR ANTAGONISTS; FOR THERAPY OF DEPRESSION, CENTRAL NERVOUS SYSTEM DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-24 | — | — | US | disclosed |