Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | GAA | P10253 | 9/20 | 0.72 |
| ▸ | HPGD | P15428 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997277 | 0.90 | ALDH1A1 (0.64) | MAPTALDH1A1GAAHPGDMEN1 | |
| Oxalic Acid SCHEMBL10858717 | 0.88 | MAPT (0.64) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL17296424 | 0.87 | MAPT (0.66) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL22392278 | 0.87 | GAA (0.69) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL22392250 | 0.87 | MAPT (0.66) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL4504119 | 0.86 | ALDH1A1 (0.67) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL970355 | 0.85 | ADORA1 (0.83) | MAPTALDH1A1GAAHPGDMEN1 | |
| Tinoridine SCHEMBL24761 | 0.84 | ADORA1 (1.00) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL6993570 | 0.84 | ADORA1 (0.84) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL10862455 | 0.84 | MAPT (0.80) | MAPTALDH1A1GAAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647725-B2 | Anti-infective 2-aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190119296-A1 | Anti-Infective 2-Aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2019-04-25 | — | — | US | disclosed |
| EP-3131890-B1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | PASTEUR INSTITUT KOREA (KR) | 2019-04-24 | — | — | EP | disclosed |
| US-9902738-B2 | Compounds and methods for preventing, treating and/or protecting against sensory hair cell death | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-02-27 | — | — | US | disclosed |
| US-9902738-B2 | Compounds and methods for preventing, treating and/or protecting against sensory hair cell death | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-02-27 | — | — | US | disclosed |
| US-9809602-B2 | Compounds for treating viral infections | INSTITUT PASTEUR KOREA (KR) | 2017-11-07 | — | — | US | disclosed |
| WO-2017184947-A1 | ANTI-INFECTIVE 2-AMINOTHIOPHENES | THE UNIVERSITY OF TOLEDO (US) | 2017-10-26 | — | — | WO | disclosed |
| EP-2900674-B1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-2900674-B1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-05-31 | — | — | EP | disclosed |
| US-20170044181-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | INSTITUT PASTEUR KOREA (KR) | 2017-02-16 | — | — | US | disclosed |
| US-9416141-B2 | Compounds and methods for preventing, treating and/or protecting against sensory hair cell death | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-08-16 | — | — | US | disclosed |
| WO-2015158908-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | INSTITUT PASTEUR KOREA (KR) | 2015-10-22 | — | — | WO | disclosed |
| US-20150232476-A1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2015-08-20 | — | — | US | disclosed |
| US-20150232476-A1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2015-08-20 | — | — | US | disclosed |
| EP-2900674-A1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | University of Washington through its Center for Commercialization (US) | 2015-08-05 | — | — | EP | disclosed |
| EP-0927184-B1 | 3-SUBSTITUTED PYRIDO 4',3':4,5]THIENO 2,3-D]PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6387912-B1 | STROKE THERAPY | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| EP-1140096-A1 | UTILIZATION OF PYRIMIDINE DERIVATIVES FOR PREVENTING AND TREATING CEREBRAL ISCHAEMIA | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-10 | — | — | EP | disclosed |
| US-6222034-B1 | AS SEROTININ RECEPTOR ANTAGONISTS; FOR THERAPY OF DEPRESSION, CENTRAL NERVOUS SYSTEM DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-24 | — | — | US | disclosed |
| WO-2000041695-A1 | UTILIZATION OF PYRIMIDINE DERIVATIVES FOR PREVENTING AND TREATING CEREBRAL ISCHAEMIA | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119296-A1 | Anti-Infective 2-Aminothiophenes | TST, ABAT, TPMT | MAPT 1615/4885ALDH1A1 2316/4885GAA 2551/4885 |
| US-10647725-B2 | Anti-infective 2-aminothiophenes | TST, ABAT, TPMT | MAPT 1615/4885ALDH1A1 2316/4885GAA 2551/4885 |
| US-20170044181-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | HAVCR2, MAVS, EIF2AK2 | MAPT 2197/4885ALDH1A1 676/4885GAA 77/4885 |
| US-20150232476-A1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | BAX, CASP3, BCL2 | MAPT 2252/4885ALDH1A1 426/4885GAA 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.