Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 16/20 | 0.57 |
| ▸ | CX3CR1 | P49238 | 15/20 | 0.57 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865679 | 0.90 | CXCR2 (0.65) | CXCR2CX3CR1PAK4 | |
| SCHEMBL6999929 | 0.89 | CXCR2 (0.53) | CXCR2CX3CR1PAK4 | |
| SCHEMBL6995579 | 0.89 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL6864634 | 0.83 | CXCR2 (0.77) | CXCR2CX3CR1 | |
| SCHEMBL6869080 | 0.79 | CX3CR1 (0.79) | CXCR2CX3CR1 | |
| SCHEMBL6866008 | 0.79 | CXCR2 (0.70) | CXCR2CX3CR1 | |
| SCHEMBL7003743 | 0.79 | CXCR2 (0.60) | CXCR2CX3CR1PAK4 | |
| SCHEMBL6866095 | 0.77 | CXCR2 (0.58) | CXCR2CX3CR1PAK4 | |
| SCHEMBL7003746 | 0.77 | CXCR2 (0.57) | CXCR2CX3CR1PAK4 | |
| SCHEMBL6866465 | 0.75 | CXCR2 (0.62) | CXCR2CX3CR1PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104425-B1 | NOVEL THIAZOLOPYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | claimed |