Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600784 | 0.83 | ERN1 (0.39) | — | |
| SCHEMBL4709591 | 0.79 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL21495061 | 0.79 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL998053 | 0.78 | CES2 (0.42) | CES2CES1 | |
| SCHEMBL2464415 | 0.78 | TUBB1 (0.38) | — | |
| SCHEMBL1701126 | 0.75 | SHBG (0.50) | CES2CES1 | |
| SCHEMBL4063849 | 0.75 | KDM1A (0.33) | — | |
| SCHEMBL20722071 | 0.74 | PSEN1 (0.35) | — | |
| SCHEMBL3973135 | 0.74 | PSEN1 (0.35) | — | |
| SCHEMBL30184822 | 0.73 | CES2 (0.39) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358169-A2 | DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-05 | — | — | EP | claimed |
| WO-2002057261-A2 | DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-25 | — | — | WO | claimed |
| EP-1358169-A2 | DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002057261-A2 | DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-25 | — | — | WO | disclosed |