Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7956777 | 0.99 | KDM1A (0.59) | KDM1ASLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL4824315 | 0.92 | KDM1A (0.54) | KDM1ASLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL6998824 | 0.91 | KDM1A (0.59) | KDM1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL7951984 | 0.90 | KDM1A (0.58) | KDM1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL18003252 | 0.83 | ALDH1A1 (0.56) | KDM1AKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL18003080 | 0.82 | ALDH1A1 (0.61) | KDM1AKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4824041 | 0.82 | ALDH1A1 (0.46) | KDM1ASLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL3135567 | 0.76 | NPY5R (0.47) | KDM1AKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL7804974 | 0.76 | HTR7 (0.47) | KDM1ASLC6A2SLC6A4ALDH1A1SLC6A3 | |
| SCHEMBL31200491 | 0.76 | ALDH1A1 (0.55) | KDM1AKDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023898-B1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | disclosed |
| EP-1023898-A1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | ADIR ET COMPAGNIE (FR) | 2000-08-02 | — | — | EP | disclosed |