Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001825 | 0.91 | DRD2 (0.65) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6780296 | 0.86 | DRD2 (0.61) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6997100 | 0.85 | DRD2 (0.65) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6993800 | 0.84 | DRD2 (0.47) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6775053 | 0.81 | DRD2 (0.59) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL20512964 | 0.79 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR6HTR7 | |
| SCHEMBL6775723 | 0.79 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6776339 | 0.79 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6780103 | 0.78 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR1AHTR6 | |
| SCHEMBL6774425 | 0.77 | DRD2 (0.71) | DRD2SLC6A4HTR2AHTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915881-B1 | PYRROLOAZEPINE COMPOUNDS | SUNTORY LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6211362-B1 | CHEMICAL INTERMEDIATE FOR DRUGS | SUNTORY LIMITED (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6187772-B1 | Pyrroloazepine compounds | SUNTORY LIMITED (JP) | 2001-02-13 | — | — | US | disclosed |