Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 13/20 | 0.50 |
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7003407 | 0.99 | CHEK1 (0.53) | CHEK1KDM4EHPGDDHODHPARP1 | |
| SCHEMBL6994637 | 0.85 | CHEK1 (0.56) | CHEK1PARP1 | |
| SCHEMBL4260461 | 0.81 | KDM4E (0.57) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL7001282 | 0.80 | CHEK1 (0.48) | CHEK1KDM4EHPGDPARP1 | |
| SCHEMBL15808131 | 0.80 | KDM4E (0.56) | CHEK1KDM4EHPGDDHODHPARP1 | |
| SCHEMBL6841606 | 0.80 | KDM4E (0.56) | KDM4EHPGDDHODHPARP1 | |
| Hydrochloric Acid SCHEMBL7000612 | 0.79 | CHEK1 (0.47) | CHEK1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4885974 | 0.78 | KDM4E (0.55) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL3790024 | 0.78 | GAA (0.58) | CHEK1KDM4E | |
| SCHEMBL8260543 | 0.77 | KDM4E (0.60) | KDM4EHPGDDHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | disclosed |
| US-6541486-B1 | Used for treating ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation. | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-01 | — | — | US | disclosed |