Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993353 | 1.00 | MEN1 (0.52) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL6994514 | 0.83 | SRD5A2 (0.51) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL6994512 | 0.83 | SRD5A2 (0.51) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL6989042 | 0.80 | ALB (0.43) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL6989039 | 0.80 | ALB (0.43) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL5670245 | 0.79 | MEN1 (0.66) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL5670247 | 0.79 | MEN1 (0.66) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL7046146 | 0.77 | MAOB (0.56) | ALOX5MAOBMAOA | |
| SCHEMBL7046152 | 0.77 | MAOB (0.56) | ALOX5MAOBMAOA | |
| SCHEMBL6995096 | 0.76 | ADORA2A (0.56) | MEN1KMT2AALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |