Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994514 | 1.00 | SRD5A2 (0.51) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6993353 | 0.83 | MEN1 (0.52) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6993349 | 0.83 | MEN1 (0.52) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6996716 | 0.81 | ALB (0.47) | MEN1NPC1RAB9AKMT2AALB | |
| SCHEMBL6996712 | 0.81 | ALB (0.47) | MEN1NPC1RAB9AKMT2AALB | |
| SCHEMBL6989986 | 0.81 | ALB (0.51) | MEN1NPC1RAB9AKMT2AALB | |
| SCHEMBL6989987 | 0.81 | ALB (0.51) | MEN1NPC1RAB9AKMT2AALB | |
| SCHEMBL6991265 | 0.80 | KMT2A (0.58) | MEN1NPC1RAB9AKMT2AALB | |
| SCHEMBL6991270 | 0.80 | KMT2A (0.58) | MEN1NPC1RAB9AKMT2AALB | |
| SCHEMBL8532502 | 0.77 | SRD5A2 (0.56) | SRD5A2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |