Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.69 |
| ▸ | PPARG | P37231 | 17/20 | 0.69 |
| ▸ | PPARD | Q03181 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103186 | 0.97 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL5105781 | 0.93 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL6696876 | 0.92 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL6991817 | 0.90 | PPARA (0.86) | PPARAPPARGPPARD | |
| SCHEMBL6700759 | 0.87 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL5105696 | 0.87 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL6699850 | 0.85 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5098886 | 0.82 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6996508 | 0.82 | PPARA (0.87) | PPARAPPARGPPARD | |
| SCHEMBL5125943 | 0.82 | PPARA (0.72) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |