Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255150 | 0.84 | MEN1 (0.34) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL30574208 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL25062278 | 0.83 | MEN1 (0.33) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL5735758 | 0.82 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL1254697 | 0.80 | ALDH1A1 (0.38) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL13193210 | 0.80 | CES2 (0.46) | MEN1KMT2ATDP1 | |
| SCHEMBL29316573 | 0.80 | CES2 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL23703846 | 0.79 | MEN1 (0.34) | MEN1KMT2ATDP1 | |
| SCHEMBL29207714 | 0.77 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL1445552 | 0.77 | MEN1 (0.31) | MEN1KMT2ATDP1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345932-A1 | DIPHENYL AZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE | Aventis Pharma Deutschland GmbH (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050068-A1 | DIPHENYL AZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-27 | — | — | WO | disclosed |