Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695922 | 1.00 | MAPT (0.41) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8717449 | 0.88 | MAPT (0.46) | MAPTMEN1KMT2ARAB9ARECQL | |
| SCHEMBL6701656 | 0.80 | ALDH1A1 (0.40) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6697703 | 0.80 | ALDH1A1 (0.40) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9174239 | 0.80 | MAPT (0.40) | MAPTRECQLALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7508194 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ARAB9ARECQL | |
| SCHEMBL3420454 | 0.80 | PTPRF (0.45) | MAPTMEN1KMT2AALDH1A1ALOX12 | |
| SCHEMBL6703753 | 0.77 | CA2 (0.40) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL1447189 | 0.77 | ALDH1A1 (0.39) | MAPTMEN1KMT2ARECQLCYP3A4 | |
| SCHEMBL11703236 | 0.77 | HPGD (0.50) | MAPTMEN1KMT2ARAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |