Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775170 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL30408858 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL21344358 | 0.82 | CA1 (0.39) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL31490117 | 0.82 | CA1 (0.39) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL2798211 | 0.82 | TAAR1 (0.53) | SMN1; SMN2TAAR1L3MBTL1 | |
| SCHEMBL18289524 | 0.81 | CA1 (0.50) | MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6906905 | 0.81 | CA1 (0.50) | MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2033633 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8207005 | 0.79 | CA1 (0.41) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL18289526 | 0.79 | CYP19A1 (0.50) | MEN1KMT2AESR1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |