Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906905 | 0.87 | CA1 (0.50) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL18289524 | 0.87 | CA1 (0.50) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL18289526 | 0.84 | CYP19A1 (0.50) | CA1CA9CA12CA2KMT2A | |
| SCHEMBL31757240 | 0.83 | CA1 (0.48) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL6823960 | 0.82 | CA1 (0.45) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL31377870 | 0.82 | CA1 (0.45) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL5966607 | 0.81 | CA12 (0.47) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL6994087 | 0.81 | LMNA (0.53) | CA1CA9CA12CA2ALDH1A1 | |
| SCHEMBL948326 | 0.80 | CNR2 (0.56) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7882874 | 0.80 | CA1 (0.44) | CA1CA9CA12CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |