Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PLG | P00747 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | PLAT | P00750 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985345 | 0.85 | CBFB (0.40) | LCKCYP3A4MAOBADORA2ARPS6KA3 | |
| Hydrochloric Acid SCHEMBL11784418 | 0.84 | EGLN1 (0.40) | LCKCYP3A4MAOBADORA2ARPS6KA3 | |
| SCHEMBL6972586 | 0.77 | HPSE (0.46) | MAOBADORA2ANPC1RAB9AHPSE | |
| Hydrochloric Acid SCHEMBL11786682 | 0.75 | HPSE (0.45) | MAOBADORA2ANPC1RAB9AHPSE | |
| Hydrochloric Acid SCHEMBL11789101 | 0.75 | HPSE (0.45) | MAOBADORA2ANPC1RAB9AHPSE | |
| SCHEMBL5924200 | 0.74 | MAOB (0.41) | LCKCYP3A4MAOBADORA2AMEN1 | |
| SCHEMBL21615514 | 0.71 | ADRB2 (0.42) | VSIRLCKRPS6KA3PARP1 | |
| SCHEMBL2946951 | 0.71 | RAB9A (0.45) | CYP3A4MAOBADORA2AMEN1NPC1 | |
| SCHEMBL6142162 | 0.71 | PARP1 (0.43) | RPS6KA3PARP1HRH4 | |
| SCHEMBL4686558 | 0.71 | MEN1 (0.52) | CYP3A4ADORA2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920314-B1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0920314-A4 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5981551-A | GRANULOCYTE COLONY-STIMULATING FACTOR MIMETICS; TREATMENT OF NEUTROPENIA | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0920314-A1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997044033-A1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-27 | — | — | WO | disclosed |