Sugi Predict

Sugi Predict / Compounds / SCHEMBL699401

SCHEMBL699401

SCHEMBL699401

Cc1cc(C)c(C=Cc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAPGEF4 Q8WZA2 7/20 0.43
▸ ABCB1 P08183 1/20 0.39
▸ HPGD P15428 1/20 0.38
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ MMP1 P03956 1/20 0.37
▸ MMP2 P08253 1/20 0.37
▸ MMP9 P14780 1/20 0.37
▸ MMP8 P22894 1/20 0.37
▸ MMP13 P45452 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP2A6 P11509 1/20 0.35
▸ FFAR4 Q5NUL3 2/20 0.33
▸ TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699400 1.00 RAPGEF4 (0.43) RAPGEF4ABCB1HPGDCA1CA2
Ammonia Solution, Strong SCHEMBL1984066 0.97 RAPGEF4 (0.41) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL23458022 0.88 RAPGEF4 (0.39) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL23458023 0.88 RAPGEF4 (0.39) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL38650688 0.83 ABCB1 (0.39) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL29194419 0.83 RAPGEF4 (0.36) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL11869228 0.83 RAPGEF4 (0.36) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL1047882 0.83 RAPGEF4 (0.36) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL11869222 0.83 RAPGEF4 (0.36) RAPGEF4ABCB1HPGDCA1CA2
SCHEMBL1047881 0.83 RAPGEF4 (0.36) RAPGEF4ABCB1HPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 — — WO disclosed
US-9868873-B2 Photochromic security enabled ink for digital offset printing applications XEROX CORPORATION (US) 2018-01-16 — — US disclosed
US-20160237101-A9 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS NATIONAL INSTITUTES OF HEALTH 2016-08-18 — — US disclosed
US-20150038724-A1 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2015-02-05 — — US disclosed
US-8846939-B2 Imidazolidine-based metal carbene metathesis catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-09-30 — — US disclosed
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 — — US disclosed
US-20130305947-A1 PHOTOCHROMIC SECURITY ENABLED INK FOR DIGITAL OFFSET PRINTING APPLICATIONS XEROX CORPORATION (US) 2013-11-21 — — US disclosed
US-8507153-B2 Compositions, optical data storage media and methods for using the optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-08-13 — — US disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 — — EP disclosed
US-20130165661-A1 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-06-27 — — US disclosed
EP-1591830-A2 Reimageable medium Xerox Corporation (US) 2005-11-02 — — EP disclosed
EP-1180108-B1 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2003-08-27 — — EP disclosed
EP-1180108-A2 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-02-20 — — EP disclosed
WO-2000071554-A2 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-11-30 — — WO disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 — — US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 — — US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 — — US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 — — US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 — — US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165661-A1 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CHRM1, CXCR6, CHRM2 RAPGEF4 3011/4885ABCB1 3849/4885HPGD 3578/4885
US-20150038724-A1 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CBR3, CBR1, INTS9 RAPGEF4 3385/4885ABCB1 4648/4885HPGD 2707/4885
US-20160237101-A9 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CBR3, CBR1, INTS9 RAPGEF4 3385/4885ABCB1 4648/4885HPGD 2707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.