Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991507 | 0.86 | KDM4E (0.48) | CYP3A4KDM4EL3MBTL1NQO2CA1 | |
| SCHEMBL17018589 | 0.84 | NAMPT (0.46) | CYP3A4KDM4EL3MBTL1NQO2LMNA | |
| SCHEMBL35210561 | 0.84 | NAMPT (0.46) | CYP3A4KDM4EL3MBTL1NQO2LMNA | |
| SCHEMBL23177724 | 0.83 | CA1 (0.47) | CYP3A4KDM4EL3MBTL1NQO2CA1 | |
| SCHEMBL28881731 | 0.82 | CYP3A4 (0.44) | CYP3A4KDM4EL3MBTL1NQO2CA1 | |
| SCHEMBL20140791 | 0.82 | CTSS (0.50) | NQO2CA1CA2CA12CA9 | |
| SCHEMBL12667243 | 0.81 | TDP1 (0.46) | CYP3A4KDM4EL3MBTL1NQO2CA1 | |
| SCHEMBL21794713 | 0.78 | TDP1 (0.50) | NQO2CA1CA2CA12CA9 | |
| SCHEMBL6554649 | 0.78 | NQO2 (0.56) | CYP3A4KDM4EL3MBTL1NQO2CA1 | |
| SCHEMBL25056476 | 0.78 | KDM4E (0.45) | CYP3A4KDM4EL3MBTL1NQO2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303488-A1 | PIPERIDINE COMPOUNDS FOR USE AS CCR-3 INHIBITORS | Novartis AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002004420-A1 | PIPERIDINE COUMPOUNDS FOR USE AS CCR-3 INHIBITORS | NOVARTIS AG (CH) | 2002-01-17 | — | — | WO | disclosed |