Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 5/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001539 | 0.88 | MAPT (0.51) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL6997430 | 0.87 | GRIA2 (0.46) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL6993715 | 0.85 | GRIA2 (0.47) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL7226645 | 0.84 | CYP1A2 (0.55) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL7453036 | 0.84 | ROCK2 (0.54) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL7228098 | 0.83 | CYP1A2 (0.62) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL6625258 | 0.82 | GRIA2 (0.61) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL6937483 | 0.80 | MAPT (0.45) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7607849 | 0.80 | CYP1A2 (0.61) | MAPTLMNAGRIA2CYP1A2CYP3A4 | |
| SCHEMBL6937957 | 0.78 | MAPT (0.44) | MAPTLMNAGRIA2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001956-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2003-05-07 | — | — | EP | disclosed |
| US-6482819-B1 | 2,3-benzodiazepine derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2002-11-19 | — | — | US | disclosed |
| EP-1001956-A1 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006408-A1 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1999-02-11 | — | — | WO | disclosed |