Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534428 | 0.83 | SRD5A2 (0.57) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8531046 | 0.81 | MCL1 (0.51) | MEN1NPC1RAB9AKMT2AMCL1 | |
| SCHEMBL8534277 | 0.80 | MCL1 (0.46) | MEN1KMT2AMCL1 | |
| SCHEMBL8531608 | 0.80 | MCL1 (0.46) | MEN1NPC1RAB9AKMT2AMCL1 | |
| SCHEMBL6994512 | 0.77 | SRD5A2 (0.51) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6994514 | 0.77 | SRD5A2 (0.51) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8534337 | 0.75 | SRD5A2 (0.46) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4470968 | 0.73 | SRD5A2 (1.00) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8000403 | 0.72 | MAOB (0.57) | SRD5A2MEN1KMT2AMAOBPTPN1 | |
| SCHEMBL4363943 | 0.72 | MAOB (0.57) | SRD5A2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |