Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813019 | 0.92 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6991189 | 0.91 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6996527 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL4820837 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6993502 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL7000368 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL976567 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6999009 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6990136 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6999259 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054888-B1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2003-11-26 | — | — | EP | claimed |
| US-6020338-A | Fungicidal 7-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-02-01 | — | — | US | claimed |
| EP-1054888-B1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1054888-A1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6020338-A | Fungicidal 7-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1999041255-A1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |