Sugi Predict

Sugi Predict / Compounds / SCHEMBL976567

SCHEMBL976567

SCHEMBL976567

Cc1nc2ncnn2c(-c2ccccc2)c1-c1c(F)cc(F)cc1F

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.48
▸ MAPK1 P28482 3/20 0.48
▸ MAPT P10636 2/20 0.48
▸ ALDH1A1 P00352 7/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ POLB P06746 2/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ENPP1 P22413 4/20 0.42
▸ TSHR P16473 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ GAA P10253 3/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ GFER P55789 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ LMNA P02545 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3227902 0.90 KDM4E (0.46) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL3217162 0.85 KDM4E (0.42) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL973763 0.85 ALDH1A1 (0.43) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL6996981 0.85 ALDH1A1 (0.43) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL6994549 0.84 ALDH1A1 (0.43) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL7000548 0.84 KDM4E (0.42) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL6994541 0.84 KDM4E (0.44) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2
SCHEMBL5731717 0.83 ALDH1A1 (0.46) KDM4EMAPK1MAPTALDH1A1POLB
SCHEMBL3223567 0.81 LSS (0.41) KDM4EMAPK1MAPTALDH1A1POLB
SCHEMBL6996527 0.81 KDM4E (0.40) KDM4EMAPK1MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741324-B2 Liquid pesticide compositions BASF SE (DE) 2014-06-03 — — US disclosed
US-8728504-B2 Process for solubilizing hydrophobic active ingredients in aqueous medium BASF SE (DE) 2014-05-20 — — US disclosed
EP-2676680-A1 Use of hydrophobin polypeptides as penetration enhancers BASF SE (DE) 2013-12-25 — — EP disclosed
US-8497230-B2 Solid crop protection agents containing polyalkoxylate, method for their production and use thereof BASF AKTIENGESELLSCHAFT (DE) 2013-07-30 — — US disclosed
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF SE (DE) 2013-05-16 — — US disclosed
EP-1763300-B1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF SE (DE) 2013-05-15 — — EP disclosed
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT BASF SE (DE) 2011-12-22 — — US disclosed
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM BASF SE (DE) 2011-08-11 — — US disclosed
EP-2308460-A1 Composition comprising active agents and at least one nitrogen-containing hyper-branched polymer BASF SE (DE) 2011-04-13 — — EP disclosed
EP-1773121-B1 LIQUID PESTICIDE COMPOSITIONS BASF SE (DE) 2011-02-09 — — EP disclosed
US-20070184983-A1 Liquid pesticide compositions BASF SE (DE) 2007-08-09 — — US disclosed
WO-2007048851-A1 SOLID CROP PROTECTION AGENTS CONTAINING POLYALKOXYLATE, METHOD FOR THEIR PRODUCTION AND USE THEREOF BASF SE (DE) 2007-05-03 — — WO disclosed
EP-1776010-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2007-04-25 — — EP disclosed
EP-1756188-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2007-02-28 — — EP disclosed
WO-2006125647-A1 METHOD FOR DETERMINING RESIDUES IN PLASTICS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006125644-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006087227-A2 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF AKTIENGESELLSCHAFT (DE) 2006-08-24 — — WO disclosed
WO-2006084680-A1 POLYMER COMPOSITIONS AND THEIR USE IN THE PRODUCTION OF ACTIVE OR EFFECTIVE INGREDIENT COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-08-17 — — WO disclosed
WO-2006015791-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 — — WO disclosed
WO-2005121201-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2005-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT PFN1, DSTN, CHN2 KDM4E 4675/4885MAPK1 3589/4885MAPT 1844/4885
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM IDUA, PHOSPHO1, HDHD5 KDM4E 4867/4885MAPK1 477/4885MAPT 2676/4885
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 KDM4E 4272/4885MAPK1 2382/4885MAPT 668/4885
US-20070184983-A1 Liquid pesticide compositions CBR3, BBC3, DDT KDM4E 3659/4885MAPK1 2845/4885MAPT 2400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.