Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 17/20 | 0.71 |
| ▸ | AR | P10275 | 2/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991539 | 1.00 | PGR (0.80) | PGRNR3C1ARNR3C2 | |
| SCHEMBL6994556 | 1.00 | PGR (0.80) | PGRNR3C1ARNR3C2 | |
| SCHEMBL7002320 | 1.00 | PGR (0.80) | PGRNR3C1ARNR3C2 | |
| SCHEMBL6291626 | 1.00 | PGR (0.80) | PGRNR3C1ARNR3C2 | |
| SCHEMBL6994720 | 1.00 | PGR (0.80) | PGRNR3C1ARNR3C2 | |
| SCHEMBL6995370 | 1.00 | PGR (0.80) | PGRNR3C1ARNR3C2 | |
| SCHEMBL6993702 | 0.90 | PGR (0.65) | PGRNR3C1ARNR3C2 | |
| SCHEMBL4177415 | 0.89 | PGR (1.00) | PGRNR3C1ARNR3C2 | |
| SCHEMBL4176728 | 0.89 | PGR (1.00) | PGRNR3C1ARNR3C2 | |
| SCHEMBL6294368 | 0.85 | NR3C1 (0.68) | PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053239-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2003-01-08 | — | — | EP | claimed |