Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994760 | 0.87 | SMN1; SMN2 (0.38) | PDE7AKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8652013 | 0.86 | KMT2A (0.40) | PDE7AKMT2AAKR1B1POLBLMNA | |
| SCHEMBL3176738 | 0.85 | PDE7A (0.35) | PDE7AKMT2APOLBNPC1 | |
| SCHEMBL8645554 | 0.84 | KMT2A (0.38) | PDE7AKMT2APOLBLMNAALDH1A1 | |
| SCHEMBL12496896 | 0.83 | PDE7A (0.40) | PDE7AKMT2APOLB | |
| SCHEMBL1721097 | 0.82 | MAPT (0.35) | KMT2AALDH1A1 | |
| SCHEMBL1153876 | 0.81 | PDE7A (0.41) | PDE7AKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2434247 | 0.81 | PDE7A (0.33) | PDE7AKMT2APOLBNPC1 | |
| SCHEMBL1475886 | 0.81 | KMT2A (0.37) | PDE7AKMT2APOLBNPC1 | |
| SCHEMBL15440893 | 0.81 | KMT2A (0.31) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0754175-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |