Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652013 | 0.86 | KMT2A (0.40) | PDE7AKMT2APOLBRAB9AMAPT | |
| SCHEMBL3176738 | 0.85 | PDE7A (0.35) | PDE7AKMT2APOLBRAB9AMAPT | |
| SCHEMBL8645554 | 0.84 | KMT2A (0.38) | PDE7AKMT2APOLBRAB9AMAPT | |
| SCHEMBL2759726 | 0.84 | ADAM17 (0.32) | — | |
| SCHEMBL12496896 | 0.83 | PDE7A (0.40) | PDE7AKMT2APOLBRAB9AMAPT | |
| SCHEMBL1475886 | 0.81 | KMT2A (0.37) | PDE7AKMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL6994973 | 0.81 | PDE7A (0.42) | PDE7AKMT2APOLBNPC1 | |
| SCHEMBL2428035 | 0.80 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL7619891 | 0.78 | THRB (0.39) | PDE7AMAPTSMN1; SMN2 | |
| SCHEMBL12496990 | 0.77 | PDE7A (0.43) | PDE7AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| EP-1989162-B1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| EP-2186791-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186805-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2184275-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-1989162-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007096058-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PIKFYVE | PDE7A 1803/4885KMT2A 936/4885HTR2A 4678/4885 |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PKM | PDE7A 1978/4885KMT2A 1396/4885HTR2A 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.